Interleukin-33 amplifies IgE synthesis and triggers mast cell degranulation via interleukin-4 in naïve mice1

BACKGROUND: The regulation and function of IgE in healthy individuals and in antigen-naïve animals is not well understood. IL-33 administration increases serum IgE in mice with unknown mechanism. We tested the hypothesis that IL-33 provides an antigen-independent stimulus for IgE production and mast...

Descripción completa

Detalles Bibliográficos
Autores principales: Komai-Koma, M, Brombacher, F, Pushparaj, P N, Arendse, B, McSharry, C, Alexander, J, Chaudhuri, R, Thomson, N C, McKenzie, A N J, McInnes, I, Liew, F Y, Xu, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660789/
https://www.ncbi.nlm.nih.gov/pubmed/22702477
http://dx.doi.org/10.1111/j.1398-9995.2012.02859.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660789/
https://www.ncbi.nlm.nih.gov/pubmed/22702477
http://dx.doi.org/10.1111/j.1398-9995.2012.02859.x

Ejemplares similares