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Viral precursor polyproteins: keys of regulation from replication to maturation

Many viruses use a replication strategy involving the translation of a large polyprotein, which is cleaved by viral and/or cellular proteases. Several of these viruses severely impact human health around the globe, including HIV, HCV, Dengue virus, and West Nile virus. This method of genome organiza...

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Detalles Bibliográficos
Autores principales: Yost, Samantha A, Marcotrigiano, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3660988/
https://www.ncbi.nlm.nih.gov/pubmed/23602469
http://dx.doi.org/10.1016/j.coviro.2013.03.009