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Mechanisms underlying restoration of hepatic insulin sensitivity with CB1 antagonism in the obese dog model
Visceral fat has long been associated with the development of insulin resistance. Although the mechanism is not well understood, it has been suggested that an increase in this fat depot results in an elevation in portal vein levels of free fatty acids and/or adipokines, adversely affecting hepatic g...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661137/ https://www.ncbi.nlm.nih.gov/pubmed/23700552 http://dx.doi.org/10.4161/adip.21890 |