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DEC-205 is a cell surface receptor for CpG oligonucleotides

We have recently demonstrated that synthetic CpG oligonucleotides (ODNs), which function as potent immunostimulators, bind to the multi-lectin receptor DEC-205, resulting in their internalization. DEC-205-deficient mice exhibit impaired dendritic-cell and B-cell maturation, impaired cytokine respons...

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Detalles Bibliográficos
Autores principales: Caminschi, Irina, Meuter, Simone, Heath, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661149/
https://www.ncbi.nlm.nih.gov/pubmed/23802064
http://dx.doi.org/10.4161/onci.23128