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A new strategy to target regulatory T cells in solid tumors

The depletion of regulatory T cells (Tregs) is a promising therapeutic strategy to enhance antitumor immune responses. Our recent findings indicate that low doses of arsenic trioxide can delay tumor growth in murine models of colon and breast cancer by depleting Tregs through oxidative and nitrosati...

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Detalles Bibliográficos
Autores principales: Thomas-Schoemann, Audrey, Batteux, Frédéric, Alexandre, Jérôme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661163/
https://www.ncbi.nlm.nih.gov/pubmed/23802078
http://dx.doi.org/10.4161/onci.23338