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Anti-GD2 antibody 3F8 and barley-derived (1 → 3),(1 → 4)-β-D-glucan: A Phase I study in patients with chemoresistant neuroblastoma

β-glucans are complex, naturally-occurring polysaccharides that prime leukocyte dectin and complement receptor 3. Based on our preclinical findings, indicating that oral barley-derived (1 → 3),(1 → 4)-β-D-glucan (BG) synergizes with the murine anti-GD2 antibody 3F8 against neuroblastoma, we conducte...

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Detalles Bibliográficos
Autores principales: Modak, Shakeel, Kushner, Brian H., Kramer, Kim, Vickers, Andrew, Cheung, Irene Y., Cheung, Nai-Kong V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661165/
https://www.ncbi.nlm.nih.gov/pubmed/23802080
http://dx.doi.org/10.4161/onci.23402