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Detecting negative selection on recurrent mutations using gene genealogy
BACKGROUND: Whether or not a mutant allele in a population is under selection is an important issue in population genetics, and various neutrality tests have been invented so far to detect selection. However, detection of negative selection has been notoriously difficult, partly because negatively s...
Autores principales: | Ezawa, Kiyoshi, Landan, Giddy, Graur, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661350/ https://www.ncbi.nlm.nih.gov/pubmed/23651527 http://dx.doi.org/10.1186/1471-2156-14-37 |
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