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Improving basic and translational science by accounting for litter-to-litter variation in animal models

BACKGROUND: Animals from the same litter are often more alike compared with animals from different litters. This litter-to-litter variation, or “litter effects”, can influence the results in addition to the experimental factors of interest. Furthermore, sometimes an experimental treatment can only b...

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Detalles Bibliográficos
Autores principales: Lazic, Stanley E, Essioux, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661356/
https://www.ncbi.nlm.nih.gov/pubmed/23522086
http://dx.doi.org/10.1186/1471-2202-14-37