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Expression of HPV16 E5 down-modulates the TGFbeta signaling pathway

BACKGROUND: Infection with high-risk human papillomavirus (HR-HPV) genotypes, mainly HPV16 and HPV18, is a major risk factor for cervical cancer and responsible for its progression. While the transforming role of the HPV E6 and E7 proteins is more characterized, the molecular mechanisms of the oncog...

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Detalles Bibliográficos
Autores principales: French, Deborah, Belleudi, Francesca, Mauro, Maria Vittoria, Mazzetta, Francesca, Raffa, Salvatore, Fabiano, Vincenza, Frega, Antonio, Torrisi, Maria Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661392/
https://www.ncbi.nlm.nih.gov/pubmed/23651589
http://dx.doi.org/10.1186/1476-4598-12-38