A Variable CD3(+) T-Cell Frequency in Peripheral Blood Lymphocytes Associated with Type 1 Diabetes Mellitus Development in the LEW.1AR1-iddm Rat

PURPOSE: The LEW.1AR1-iddm rat is an animal model of human type 1 diabetes mellitus (T1DM), which arose through a spontaneous mutation within the MHC-congenic inbred strain LEW.1AR1 (RT1(r2)). In contrast to the diabetes-resistant LEW.1AR1 background strain in LEW.1AR1-iddm rats a highly variable T-...

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Detalles Bibliográficos
Autores principales: Arndt, Tanja, Jörns, Anne, Weiss, Heike, Tiedge, Markus, Hedrich, Hans-Jürgen, Lenzen, Sigurd, Wedekind, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661438/
https://www.ncbi.nlm.nih.gov/pubmed/23717591
http://dx.doi.org/10.1371/journal.pone.0064305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661438/
https://www.ncbi.nlm.nih.gov/pubmed/23717591
http://dx.doi.org/10.1371/journal.pone.0064305

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