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PGC-1α Is Required for Exercise- and Exercise Training-Induced UCP1 Up-Regulation in Mouse White Adipose Tissue

BACKGROUND: The aim of the present study was to test the hypotheses that 1) a single exercise bout increases UCP1 mRNA in both inguinal (i)WAT and epididymal (e)WAT, 2) UCP1 expression and responsiveness to exercise are different in iWAT and eWAT, 3) PGC-1α determines the basal levels of UCP1 and PR...

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Detalles Bibliográficos
Autores principales: Ringholm, Stine, Grunnet Knudsen, Jakob, Leick, Lotte, Lundgaard, Anders, Munk Nielsen, Maja, Pilegaard, Henriette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661446/
https://www.ncbi.nlm.nih.gov/pubmed/23717545
http://dx.doi.org/10.1371/journal.pone.0064123