A Functional Yeast Survival Screen of Tumor-Derived cDNA Libraries Designed to Identify Anti-Apoptotic Mammalian Oncogenes

Yeast cells can be killed upon expression of pro-apoptotic mammalian proteins. We have established a functional yeast survival screen that was used to isolate novel human anti-apoptotic genes overexpressed in treatment-resistant tumors. The screening of three different cDNA libraries prepared from m...

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Detalles Bibliográficos
Autores principales: Eißmann, Moritz, Schwamb, Bettina, Melzer, Inga Maria, Moser, Julia, Siele, Dagmar, Köhl, Ulrike, Rieker, Ralf Joachim, Wachter, David Lukas, Agaimy, Abbas, Herpel, Esther, Baumgarten, Peter, Mittelbronn, Michel, Rakel, Stefanie, Kögel, Donat, Böhm, Stefanie, Gutschner, Tony, Diederichs, Sven, Zörnig, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661464/
https://www.ncbi.nlm.nih.gov/pubmed/23717670
http://dx.doi.org/10.1371/journal.pone.0064873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661464/
https://www.ncbi.nlm.nih.gov/pubmed/23717670
http://dx.doi.org/10.1371/journal.pone.0064873

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