Proinflammatory Cytokines and Bile Acids Upregulate ΔNp73 Protein, an Inhibitor of p53 and p73 Tumor Suppressors

Gastroesophageal reflux disease (GERD) is the main etiological factor behind the recent rapid increase in the incidence of esophageal adenocarcinoma. During reflux, esophageal cells are exposed to bile at low pH resulting in cellular damage and inflammation, which are known to facilitate cancer deve...

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Detalles Bibliográficos
Autores principales: Zaika, Elena, Bhardwaj, Vikas, Wei, Jinxiong, Washington, Mary Kay, Souza, Rhonda, El-Rifai, Wael, Zaika, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661465/
https://www.ncbi.nlm.nih.gov/pubmed/23717592
http://dx.doi.org/10.1371/journal.pone.0064306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661465/
https://www.ncbi.nlm.nih.gov/pubmed/23717592
http://dx.doi.org/10.1371/journal.pone.0064306

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