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In Vivo Monitoring of Multi-Unit Neural Activity in the Suprachiasmatic Nucleus Reveals Robust Circadian Rhythms in Period1(−/−) Mice

The master pacemaker in the suprachiasmatic nucleus (SCN) controls daily rhythms of behavior in mammals. C57BL/6J mice lacking Period1 (Per1(−/−)) are an anomaly because their SCN molecular rhythm is weak or absent in vitro even though their locomotor activity rhythm is robust. To resolve the contra...

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Detalles Bibliográficos
Autores principales: Takasu, Nana N., Pendergast, Julie S., Olivas, Cathya S., Yamazaki, Shin, Nakamura, Wataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661484/
https://www.ncbi.nlm.nih.gov/pubmed/23717599
http://dx.doi.org/10.1371/journal.pone.0064333