Potent Suppression of Kv1.3 Potassium Channel and IL-2 Secretion by Diphenyl Phosphine Oxide-1 in Human T Cells

Diphenyl phosphine oxide-1 (DPO-1) is a potent Kv1.5 channel inhibitor that has therapeutic potential for the treatment of atrial fibrillation. Many other Kv1.5 channel blockers also potently inhibit the Kv1.3 channel, but whether DPO-1 blocks Kv1.3 channels has not been investigated. The Kv1.3 chan...

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Detalles Bibliográficos
Autores principales: Zhao, Ning, Dong, Qian, Du, Li-Li, Fu, Xiao-Xing, Du, Yi-Mei, Liao, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661503/
https://www.ncbi.nlm.nih.gov/pubmed/23717641
http://dx.doi.org/10.1371/journal.pone.0064629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661503/
https://www.ncbi.nlm.nih.gov/pubmed/23717641
http://dx.doi.org/10.1371/journal.pone.0064629

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