A Robust Strategy for Negative Selection of Cre-LoxP Recombination-Based Excision of Transgenes in Induced Pluripotent Stem Cells

Viral vectors remain the most efficient and popular in deriving induced pluripotent stem cells (iPSCs). For translation, it is important to silence or remove the reprogramming factors after induction of pluripotency. In this study, we design an excisable loxP-flanked lentiviral construct that a) inc...

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Detalles Bibliográficos
Autores principales: Chakraborty, Syandan, Christoforou, Nicolas, Fattahi, Ali, Herzog, Roland W., Leong, Kam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661507/
https://www.ncbi.nlm.nih.gov/pubmed/23717601
http://dx.doi.org/10.1371/journal.pone.0064342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661507/
https://www.ncbi.nlm.nih.gov/pubmed/23717601
http://dx.doi.org/10.1371/journal.pone.0064342

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