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The Polarization of the G-Protein Activated Potassium Channel GIRK5 to the Vegetal Pole of Xenopus laevis Oocytes Is Driven by a Di-Leucine Motif

The G protein-coupled inwardly-rectifying potassium channels (known as GIRK or Kir3) form functional heterotetramers gated by G-βγ subunits. GIRK channels participate in heart rate modulation and neuronal postsynaptic inhibition in mammals. In Xenopus laevis oocytes, GIRK5 is a functional homomultim...

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Detalles Bibliográficos
Autores principales: Díaz-Bello, Beatriz, Rangel-García, Claudia I., Salvador, Carolina, Carrisoza-Gaytán, Rolando, Escobar, Laura I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661522/
https://www.ncbi.nlm.nih.gov/pubmed/23717539
http://dx.doi.org/10.1371/journal.pone.0064096