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Decreased MicroRNA Is Involved in the Vascular Remodeling Abnormalities in Chronic Kidney Disease (CKD)

Patients with CKD have abnormal vascular remodeling that is a risk factor for cardiovascular disease. MicroRNAs (miRNAs) control mRNA expression intracellularly and are secreted into the circulation; three miRNAs (miR-125b, miR-145 and miR-155) are known to alter vascular smooth muscle cell (VSMC) p...

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Detalles Bibliográficos
Autores principales: Chen, Neal X., Kiattisunthorn, Kraiwiporn, O'Neill, Kalisha D., Chen, Xianming, Moorthi, Ranjani N., Gattone, Vincent H., Allen, Matthew R., Moe, Sharon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661525/
https://www.ncbi.nlm.nih.gov/pubmed/23717629
http://dx.doi.org/10.1371/journal.pone.0064558