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An Enzyme-Generated Fragment of Tau Measured in Serum Shows an Inverse Correlation to Cognitive Function

OBJECTIVE: Alzheimer's disease (AD) is a devastating neurological disease characterized by pathological proteolytic cleavage of tau protein, which appears to initiate death of the neurons. The objective of this study was to investigate whether a proteolytic fragment of the tau protein could ser...

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Detalles Bibliográficos
Autores principales: Henriksen, Kim, Wang, Yaguo, Sørensen, Mette G., Barascuk, Natasha, Suhy, Joyce, Pedersen, Jan T., Duffin, Kevin L., Dean, Robert A., Pajak, Monika, Christiansen, Claus, Zheng, Qinlong, Karsdal, Morten A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661565/
https://www.ncbi.nlm.nih.gov/pubmed/23717682
http://dx.doi.org/10.1371/journal.pone.0064990