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An Enzyme-Generated Fragment of Tau Measured in Serum Shows an Inverse Correlation to Cognitive Function
OBJECTIVE: Alzheimer's disease (AD) is a devastating neurological disease characterized by pathological proteolytic cleavage of tau protein, which appears to initiate death of the neurons. The objective of this study was to investigate whether a proteolytic fragment of the tau protein could ser...
Autores principales: | Henriksen, Kim, Wang, Yaguo, Sørensen, Mette G., Barascuk, Natasha, Suhy, Joyce, Pedersen, Jan T., Duffin, Kevin L., Dean, Robert A., Pajak, Monika, Christiansen, Claus, Zheng, Qinlong, Karsdal, Morten A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661565/ https://www.ncbi.nlm.nih.gov/pubmed/23717682 http://dx.doi.org/10.1371/journal.pone.0064990 |
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