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AMPK Is Involved in the Regulation of Incretin Receptors Expression in Pancreatic Islets under a Low Glucose Concentration

The precise role of AMP-activated protein kinase (AMPK), a target of metformin, in pancreatic β cells remains controversial, even though metformin was recently shown to enhance the expression of incretin receptors (GLP-1 and GIP receptors) in pancreatic β cells. In this study, we investigated the ef...

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Detalles Bibliográficos
Autores principales: Tajima, Kazuki, Shirakawa, Jun, Togashi, Yu, Inoue, Hideaki, Sato, Koichiro, Orime, Kazuki, Ito, Yuzuru, Kaji, Mitsuyo, Sakamoto, Eri, Nakamura, Akinobu, Aoki, Kazutaka, Goshima, Yoshio, Atsumi, Tatsuya, Terauchi, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661597/
https://www.ncbi.nlm.nih.gov/pubmed/23717642
http://dx.doi.org/10.1371/journal.pone.0064633