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Decreased RB1 mRNA, Protein, and Activity Reflect Obesity-Induced Altered Adipogenic Capacity in Human Adipose Tissue

Retinoblastoma (Rb1) has been described as an essential player in white adipocyte differentiation in mice. No studies have been reported thus far in human adipose tissue or human adipocytes. We aimed to investigate the possible role and regulation of RB1 in adipose tissue in obesity using human samp...

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Detalles Bibliográficos
Autores principales: Moreno-Navarrete, José María, Petrov, Petar, Serrano, Marta, Ortega, Francisco, García-Ruiz, Estefanía, Oliver, Paula, Ribot, Joan, Ricart, Wifredo, Palou, Andreu, Bonet, Mª Luisa, Fernández-Real, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661645/
https://www.ncbi.nlm.nih.gov/pubmed/23315497
http://dx.doi.org/10.2337/db12-0977