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APOBEC3G-Augmented Stem Cell Therapy to Modulate HIV Replication: A Computational Study
The interplay between the innate immune system restriction factor APOBEC3G and the HIV protein Vif is a key host-retrovirus interaction. APOBEC3G can counteract HIV infection in at least two ways: by inducing lethal mutations on the viral cDNA; and by blocking steps in reverse transcription and vira...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661658/ https://www.ncbi.nlm.nih.gov/pubmed/23724012 http://dx.doi.org/10.1371/journal.pone.0063984 |