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Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome

It has been established that Adenosine-5'-triphosphate (ATP) can activate the NLRP3 inflammasome. However, the physiological effect of extracellular ATP on NLRP3 inflammasome activation has not yet been investigated. In the present study, we found that ATP was indeed released during bacterial i...

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Detalles Bibliográficos
Autores principales: Xiang, Yang, Wang, Xuan, Yan, Chao, Gao, Qian, Li, Sheng-An, Liu, Jie, Zhou, Kaifeng, Guo, Xiaolong, Lee, Wenhui, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661663/
https://www.ncbi.nlm.nih.gov/pubmed/23717478
http://dx.doi.org/10.1371/journal.pone.0063759