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Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Chaperone-mediated autophagy (CMA) contributes to cellular quality control and the cellular response to stress through the selective degradation of cytosolic proteins in lysosomes. Decrease in CMA activity occurs in aging and in age-related disorders (for example, neurodegenerative diseases and diab...

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Detalles Bibliográficos
Autores principales: Anguiano, Jaime, Garner, Thomas P, Mahalingam, Murugesan, Das, Bhaskar C., Gavathiotis, Evripidis, Cuervo, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661710/
https://www.ncbi.nlm.nih.gov/pubmed/23584676
http://dx.doi.org/10.1038/nchembio.1230