Cargando…

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

Chaperone-mediated autophagy (CMA) contributes to cellular quality control and the cellular response to stress through the selective degradation of cytosolic proteins in lysosomes. Decrease in CMA activity occurs in aging and in age-related disorders (for example, neurodegenerative diseases and diab...

Descripción completa

Detalles Bibliográficos
Autores principales:	Anguiano, Jaime, Garner, Thomas P, Mahalingam, Murugesan, Das, Bhaskar C., Gavathiotis, Evripidis, Cuervo, Ana Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661710/ https://www.ncbi.nlm.nih.gov/pubmed/23584676 http://dx.doi.org/10.1038/nchembio.1230

Ejemplares similares

Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration
por: Gomez-Sintes, Raquel, et al.
Publicado: (2022)

Chaperone-mediated autophagy regulates adipocyte differentiation
por: Kaushik, Susmita, et al.
Publicado: (2022)

Chaperone-Mediated Autophagy Upregulation Rescues Megalin Expression and Localization in Cystinotic Proximal Tubule Cells
por: Zhang, Jinzhong, et al.
Publicado: (2019)

Humanin is an endogenous activator of chaperone-mediated autophagy
por: Gong, Zhenwei, et al.
Publicado: (2018)

Chaperone-mediated autophagy sustains hematopoietic stem cell function
por: Dong, S, et al.
Publicado: (2021)

Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide
por: Macri, Christophe, et al.
Publicado: (2015)

A Forward Chemical Screen in Zebrafish Identifies a Retinoic Acid Derivative with Receptor Specificity
por: Das, Bhaskar C., et al.
Publicado: (2010)

Chaperone-mediated autophagy protects against atherosclerosis
por: Madrigal-Matute, Julio, et al.
Publicado: (2022)

Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
por: Kaushik, Susmita, et al.
Publicado: (2015)

Pulling the BAX trigger for tumor cell death
por: Reyna, Denis E., et al.
Publicado: (2018)

Self-regulation of BAX-induced cell death
por: Reyna, Denis E., et al.
Publicado: (2016)

Regulated Degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage
por: Park, Caroline, et al.
Publicado: (2015)

Loss of hepatic chaperone-mediated autophagy accelerates proteostasis failure in aging
por: Schneider, Jaime L, et al.
Publicado: (2015)

A photoconvertible fluorescent reporter to track chaperone-mediated autophagy
por: Koga, Hiroshi, et al.
Publicado: (2011)

Eltrombopag directly inhibits BAX and prevents cell death
por: Spitz, Adam Z., et al.
Publicado: (2021)

Interplay of LRRK2 with chaperone-mediated autophagy
por: Orenstein, Samantha J., et al.
Publicado: (2013)

Proteome-wide analysis of chaperone-mediated autophagy targeting motifs
por: Kirchner, Philipp, et al.
Publicado: (2019)

Effects of retinoic acid receptor α modulators on developmental ethanol-induced neurodegeneration and neuroinflammation
por: Saito, Mariko, et al.
Publicado: (2023)

Small Molecule Allosteric Inhibitors of BAX
por: Garner, Thomas P., et al.
Publicado: (2019)

Monitoring spatiotemporal changes in chaperone-mediated autophagy in vivo
por: Dong, S., et al.
Publicado: (2020)

Transcription factor NFE2L2/NRF2 modulates chaperone-mediated autophagy through the regulation of LAMP2A
por: Pajares, Marta, et al.
Publicado: (2018)

Correction: Proteome-wide analysis of chaperone-mediated autophagy targeting motifs
por: Kirchner, Philipp, et al.
Publicado: (2022)

Reciprocal regulation of chaperone-mediated autophagy and the circadian clock
por: Juste, Yves R., et al.
Publicado: (2021)

Retinoic Acid and Its Role in Modulating Intestinal Innate Immunity
por: Czarnewski, Paulo, et al.
Publicado: (2017)

Chemical Chaperones Modulate the Formation of Metabolite Assemblies
por: Adsi, Hanaa, et al.
Publicado: (2021)

Retinoic Acid and Its Derivatives in Skin
por: Szymański, Łukasz, et al.
Publicado: (2020)

Modulating Chaperone-Mediated Autophagy and Its Clinical Applications in Cancer
por: Hubert, Virginie, et al.
Publicado: (2022)

Retinoic acid induces differentiation in neuroblastoma via ROR1 by modulating retinoic acid response elements
por: Illendula, Abhinav, et al.
Publicado: (2020)

Retinoic Acid as a Modulator of T Cell Immunity
por: Bono, Maria Rosa, et al.
Publicado: (2016)

Novel Retinoic Acid Receptor Alpha Agonists for Treatment of Kidney Disease
por: Zhong, Yifei, et al.
Publicado: (2011)

Protective role of chaperone-mediated autophagy against atherosclerosis
por: Madrigal-Matute, Julio, et al.
Publicado: (2022)

αA-Crystallin–Derived Mini-Chaperone Modulates Stability and Function of Cataract Causing αAG98R-Crystallin
por: Raju, Murugesan, et al.
Publicado: (2012)

Chaperone mediated autophagy regulates T cell responses through targeted degradation of negative regulators of T cell activation
por: Valdor, Rut, et al.
Publicado: (2014)

Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy
por: Valdor, Rut, et al.
Publicado: (2019)

Chaperone-mediated autophagy: roles in neurodegeneration
por: Wang, Gang, et al.
Publicado: (2014)

Retinoic Acid Alleviates Cisplatin-Induced Acute Kidney Injury Through Activation of Autophagy
por: Wu, Junxia, et al.
Publicado: (2020)

Marinopyrrole Derivatives with Sulfide Spacers as Selective Disruptors of Mcl-1 Binding to Pro-Apoptotic Protein Bim
por: Cheng, Chunwei, et al.
Publicado: (2014)

Retinoic Acid Embryopathy
por: Mondal, Dipankar, et al.
Publicado: (2017)

FRC-derived retinoic acid: The key to unlocking milky spots
por: Daley, Alexander D., et al.
Publicado: (2023)

Chaperone-Mediated Autophagy Controls Proteomic and Transcriptomic Pathways to Maintain Glioma Stem Cell Activity
por: Auzmendi-Iriarte, Jaione, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gei2kksadlpea0vhem106utelk