Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments

Protein structures evolved through a complex interplay of cooperative interactions and it is still very challenging to design new protein folds de novo. Here, we present a strategy to design self-assembling polypeptide nanostructured polyhedra, based on modularization using orthogonal dimerizing seg...

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Detalles Bibliográficos
Autores principales: Gradišar, Helena, Božič, Sabina, Doles, Tibor, Vengust, Damjan, Hafner-Bratkovič, Iva, Mertelj, Alenka, Webb, Ben, Šali, Andrej, Klavžar, Sandi, Jerala, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661711/
https://www.ncbi.nlm.nih.gov/pubmed/23624438
http://dx.doi.org/10.1038/nchembio.1248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661711/
https://www.ncbi.nlm.nih.gov/pubmed/23624438
http://dx.doi.org/10.1038/nchembio.1248

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