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Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments
Protein structures evolved through a complex interplay of cooperative interactions and it is still very challenging to design new protein folds de novo. Here, we present a strategy to design self-assembling polypeptide nanostructured polyhedra, based on modularization using orthogonal dimerizing seg...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661711/ https://www.ncbi.nlm.nih.gov/pubmed/23624438 http://dx.doi.org/10.1038/nchembio.1248 |