A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection

Expression of the programmed death 1 (PD-1) receptor and its ligands are implicated in the T cell exhaustion phenotype which contributes to the persistence of several chronic viral infections, including human hepatitis C virus (HCV). The antiviral potential of BMS-936558 (MDX-1106) – a fully human a...

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Detalles Bibliográficos
Autores principales: Gardiner, David, Lalezari, Jay, Lawitz, Eric, DiMicco, Michael, Ghalib, Rheem, Reddy, K. Rajender, Chang, Kyong-Mi, Sulkowski, Mark, Marro, Steven O’, Anderson, Jeffrey, He, Bing, Kansra, Vikram, McPhee, Fiona, Wind-Rotolo, Megan, Grasela, Dennis, Selby, Mark, Korman, Alan J., Lowy, Israel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661719/
https://www.ncbi.nlm.nih.gov/pubmed/23717490
http://dx.doi.org/10.1371/journal.pone.0063818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661719/
https://www.ncbi.nlm.nih.gov/pubmed/23717490
http://dx.doi.org/10.1371/journal.pone.0063818

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