Cargando…

A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection

Expression of the programmed death 1 (PD-1) receptor and its ligands are implicated in the T cell exhaustion phenotype which contributes to the persistence of several chronic viral infections, including human hepatitis C virus (HCV). The antiviral potential of BMS-936558 (MDX-1106) – a fully human a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gardiner, David, Lalezari, Jay, Lawitz, Eric, DiMicco, Michael, Ghalib, Rheem, Reddy, K. Rajender, Chang, Kyong-Mi, Sulkowski, Mark, Marro, Steven O’, Anderson, Jeffrey, He, Bing, Kansra, Vikram, McPhee, Fiona, Wind-Rotolo, Megan, Grasela, Dennis, Selby, Mark, Korman, Alan J., Lowy, Israel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661719/ https://www.ncbi.nlm.nih.gov/pubmed/23717490 http://dx.doi.org/10.1371/journal.pone.0063818

Ejemplares similares

Peripheral blood and tumor biomarkers in patients with advanced melanoma treated with combination nivolumab (anti-PD-1, BMS-936558, ONO-4538) and ipilimumab
por: Callahan, Margaret K, et al.
Publicado: (2013)

Peripheral and tumor immune correlates in patients with advanced melanoma treated with nivolumab (anti-PD-1, BMS-936558, ONO-4538) monotherapy or in combination with ipilimumab
por: Postow, Michael A, et al.
Publicado: (2014)

An open-label, multiple ascending dose study of the anti-CTLA-4 antibody ipilimumab in viremic HIV patients
por: Colston, Elizabeth, et al.
Publicado: (2018)

Dapagliflozin: BMS 512148; BMS-512148
Publicado: (2012)

Crystal structures of trimeric HIV Env with entry inhibitors BMS-378806 and BMS-626529
por: Pancera, Marie, et al.
Publicado: (2017)

Barrel-muon-spectrometer: BMS
Publicado: (2005)

Barrel-muon-spectrometer: BMS
Publicado: (2005)

Barrel-muon-spectrometer: BMS
Publicado: (2005)

Barrel-muon-spectrometer: BMS
Publicado: (2005)

Barrel-muon-spectrometer: BMS
Publicado: (2005)

Barrel-muon-spectrometer: BMS
Publicado: (2005)

Barrel-muon-spectrometer: BMS
Publicado: (2005)

Safety, pharmacokinetics and pharmacodynamics of branebrutinib (BMS‐986195), a covalent, irreversible inhibitor of Bruton's tyrosine kinase: Randomised phase I, placebo‐controlled trial in healthy participants
por: Catlett, Ian M., et al.
Publicado: (2020)

Pharmacokinetics, safety, and tolerability of BMS‐986263, a lipid nanoparticle containing HSP47 siRNA, in participants with hepatic impairment
por: Qosa, Hisham, et al.
Publicado: (2023)

HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 sub-group analysis
por: Brinson, Cynthia, et al.
Publicado: (2014)

540 HIV-1 Attachment Inhibitor Prodrug BMS-663068 in Antiretroviral-Experienced Subjects: Week 24 Subgroup Analysis
por: Brinson, Cynthia, et al.
Publicado: (2014)

Safety profile of HIV-1 attachment inhibitor prodrug BMS-663068 in antiretroviral-experienced subjects: week 24 analysis
por: Lalezari, Jacob, et al.
Publicado: (2014)

Construction of the MPI BMS Prototype Chamber
por: Bratzler, U, et al.
Publicado: (1997)

1574 Safety Profile of HIV-1 Attachment Inhibitor Prodrug BMS-663068 in Antiretroviral-Experienced Subjects: Week 24 Analysis
por: Lalezari, Jacob, et al.
Publicado: (2014)

BMS‐986263 in patients with advanced hepatic fibrosis: 36‐week results from a randomized, placebo‐controlled phase 2 trial
por: Lawitz, Eric J., et al.
Publicado: (2021)

Beneficial effect of fluorocarbon emulsion media on the function of neuromuscular preparations in vitro
por: Wong, SS, et al.
Publicado: (1977)

BMS1 Is Mutated in Aplasia Cutis Congenita
por: Marneros, Alexander G.
Publicado: (2013)

Role of Mitochondrial Toxicity in BMS-986094-Induced Toxicity
por: Feng, Joy Y., et al.
Publicado: (2017)

Effect of BMS-470539 on lipopolysaccharide-induced neutrophil activation
por: Lee, Seongheon, et al.
Publicado: (2020)

Phase I study of the mitomycin C analogue BMS-181174.
por: Macaulay, V. M., et al.
Publicado: (1998)

Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780
por: Toyn, Jeremy H., et al.
Publicado: (2014)

A Behaviour Monitoring System (BMS) for Ambient Assisted Living
por: Eisa, Samih, et al.
Publicado: (2017)

The effects of BMS-470539 on lipopolysaccharide-induced acute lung injury
por: Jang, Eun-A, et al.
Publicado: (2019)

The Effectiveness and Adverse Events of Amitriptyline and Aripiprazole in Very Elderly Patients With BMS
por: Watanabe, Motoko, et al.
Publicado: (2022)

ACCELERATED AGING AMONG ADULTS LIVING WITH CEREBRAL PALSY
por: Peterson, Mark, et al.
Publicado: (2022)

Mastering Kali Linux for Web penetration testing: test and evaluate all aspects of the design and implementation
por: McPhee, Michael
Publicado: (2017)

The curve of binding energy: a journey into awesome and alarming world of Theodore B. Taylor
por: McPhee, John
Publicado: (1974)

Mastering Strategic Risk: A Framework for Leading and Transforming Organizations
por: McPhee, Joel
Publicado: (2014)

Withdrawn Paper: Antibacterial Effect of Five Zingiberaceae Essential Oils by Laohakunjit et al., Molecules 2007, 12, 2047-2060
por: McPhee, Derek
Publicado: (2008)

Retraction: Agarwal et al. Dynamic Action of Carotenoids in Cardioprotection and Maintenance of Cardiac Health, Molecules 2012, 17, 4755-4769
por: McPhee, Derek
Publicado: (2014)

A New Editor in Chief for Molecules (It’s Been a Fun Ride)
por: McPhee, Derek
Publicado: (2020)

THE FORMULA FOR CARDIOVASCULAR HEALTH AND WELL-BEING IN ADULTS WITH CEREBRAL PALSY
por: McPhee, Patrick
Publicado: (2022)

All-Oral 12-Week Treatment With Daclatasvir Plus Sofosbuvir in Patients With Hepatitis C Virus Genotype 3 Infection: ALLY-3 Phase III Study
por: Nelson, David R, et al.
Publicado: (2015)

Characterization of a BMS-181174-resistant human bladder cancer cell line.
por: Xia, H., et al.
Publicado: (1997)

Comparison of coronary DES and BMS in octogenarians: A systematic review and meta-analysis
por: Gao, Lei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_inqqk3ojqqqvijt6qpdaq4roge