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Iron-Ascorbate-Mediated Lipid Peroxidation Causes Epigenetic Changes in the Antioxidant Defense in Intestinal Epithelial Cells: Impact on Inflammation

INTRODUCTION: The gastrointestinal tract is frequently exposed to noxious stimuli that may cause oxidative stress, inflammation and injury. Intraluminal pro-oxidants from ingested nutrients especially iron salts and ascorbic acid frequently consumed together, can lead to catalytic formation of oxyge...

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Detalles Bibliográficos
Autores principales: Yara, Sabrina, Lavoie, Jean-Claude, Beaulieu, Jean-François, Delvin, Edgard, Amre, Devendra, Marcil, Valerie, Seidman, Ernest, Levy, Emile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661745/
https://www.ncbi.nlm.nih.gov/pubmed/23717425
http://dx.doi.org/10.1371/journal.pone.0063456