Structure of a class II preQ(1) riboswitch reveals ligand recognition by a new fold

PreQ(1) riboswitches regulate genes by binding the pyrrolopyrimidine intermediate preQ(1) during biosynthesis of the essential tRNA base queuosine. We report the first preQ(1)-II riboswitch structure at 2.3 Å resolution, which uses a novel fold to achieve effector recognition at the confluence of a...

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Detalles Bibliográficos
Autores principales: Liberman, Joseph A., Salim, Mohammad, Krucinska, Jolanta, Wedekind, Joseph E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661761/
https://www.ncbi.nlm.nih.gov/pubmed/23584677
http://dx.doi.org/10.1038/nchembio.1231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661761/
https://www.ncbi.nlm.nih.gov/pubmed/23584677
http://dx.doi.org/10.1038/nchembio.1231

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