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Structure of a class II preQ(1) riboswitch reveals ligand recognition by a new fold
PreQ(1) riboswitches regulate genes by binding the pyrrolopyrimidine intermediate preQ(1) during biosynthesis of the essential tRNA base queuosine. We report the first preQ(1)-II riboswitch structure at 2.3 Å resolution, which uses a novel fold to achieve effector recognition at the confluence of a...
Autores principales: | Liberman, Joseph A., Salim, Mohammad, Krucinska, Jolanta, Wedekind, Joseph E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661761/ https://www.ncbi.nlm.nih.gov/pubmed/23584677 http://dx.doi.org/10.1038/nchembio.1231 |
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