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Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats

Pro-nociceptive ON-cells in the rostral ventromedial medulla (RVM) facilitate nociceptive processing and contribute to descending serotonergic controls. We use RVM injections of neurotoxic dermorphin-saporin (Derm-SAP) in rats to evaluate the role of putative ON-cells, or μ-opioid receptor-expressin...

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Detalles Bibliográficos
Autores principales: Sikandar, Shafaq, Bannister, Kirsty, Dickenson, Anthony H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661978/
https://www.ncbi.nlm.nih.gov/pubmed/22579856
http://dx.doi.org/10.1016/j.neulet.2012.05.009