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Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats
Pro-nociceptive ON-cells in the rostral ventromedial medulla (RVM) facilitate nociceptive processing and contribute to descending serotonergic controls. We use RVM injections of neurotoxic dermorphin-saporin (Derm-SAP) in rats to evaluate the role of putative ON-cells, or μ-opioid receptor-expressin...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific Publishers Ireland
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661978/ https://www.ncbi.nlm.nih.gov/pubmed/22579856 http://dx.doi.org/10.1016/j.neulet.2012.05.009 |