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A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease

Peroxisome proliferator-activated receptor (PPAR)-γ and PPARα have shown neuroprotective effects in models of Parkinson’s disease (PD). The role of the third, more ubiquitous isoform PPARδ has not been fully explored. This study investigated the role of PPARδ in PD using 1-methyl-4-phenyl-1,2,3,6-te...

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Detalles Bibliográficos
Autores principales: Martin, H.L., Mounsey, R.B., Sathe, K., Mustafa, S., Nelson, M.C., Evans, R.M., Teismann, P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661980/
https://www.ncbi.nlm.nih.gov/pubmed/23500098
http://dx.doi.org/10.1016/j.neuroscience.2013.02.058