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NAG-1/GDF15 Transgenic Mouse Has Less White Adipose Tissue and a Reduced Inflammatory Response

NAG-1/GDF15 is a TGF-β superfamily member with poorly characterized biological activity proposed to inhibit inflammatory cytokine production. Transgenic mice expressing human NAG-1/GDF15 (NAG-1(Tg/Lox)) are leaner with lower body weight and are resistant to chemically or genetically induced intestin...

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Detalles Bibliográficos
Autores principales: Kim, J. M., Kosak, J. P., Kim, J. K., Kissling, G., Germolec, D. R., Zeldin, D. C., Bradbury, J. A., Baek, S. J., Eling, T. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662179/
https://www.ncbi.nlm.nih.gov/pubmed/23737651
http://dx.doi.org/10.1155/2013/641851