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Stathmin regulates mutant p53 stability and transcriptional activity in ovarian cancer

Stathmin is a p53-target gene, frequently overexpressed in late stages of human cancer progression. Type II High Grade Epithelial Ovarian Carcinomas (HG-EOC) represents the only clear exception to this observation. Here, we show that stathmin expression is necessary for the survival of HG-EOC cells...

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Detalles Bibliográficos
Autores principales: Sonego, Maura, Schiappacassi, Monica, Lovisa, Sara, Dall'Acqua, Alessandra, Bagnoli, Marina, Lovat, Francesca, Libra, Massimo, D'Andrea, Sara, Canzonieri, Vincenzo, Militello, Loredana, Napoli, Marco, Giorda, Giorgio, Pivetta, Barbara, Mezzanzanica, Delia, Barbareschi, Mattia, Valeri, Barbara, Canevari, Silvana, Colombatti, Alfonso, Belletti, Barbara, Del Sal, Giannino, Baldassarre, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662314/
https://www.ncbi.nlm.nih.gov/pubmed/23610071
http://dx.doi.org/10.1002/emmm.201201504