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SRSF1 and SRSF9 RNA binding proteins promote Wnt signalling-mediated tumorigenesis by enhancing β-catenin biosynthesis

Wnt/β-catenin signalling is widely implicated in embryogenesis, tissue homeostasis and tumorigenesis. The key event in Wnt signalling activation is β-catenin accumulation, which is controlled by both its production and degradation. However, much more emphasis has been placed on the understanding of...

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Detalles Bibliográficos
Autores principales: Fu, Yu, Huang, Binlu, Shi, Zhen, Han, Jiayu, Wang, Ying, Huangfu, Jieqiong, Wu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662316/
https://www.ncbi.nlm.nih.gov/pubmed/23592547
http://dx.doi.org/10.1002/emmm.201202218