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R5 HIV-1 envelope attracts dendritic cells to cross the human intestinal epithelium and sample luminal virions via engagement of the CCR5

The gastrointestinal tract is a principal route of entry and site of persistence of human immunodeficiency virus type 1 (HIV-1). The intestinal mucosa, being rich of cells that are the main target of the virus, represents a primary site of viral replication and CD4(+) T-cell depletion. Here, we show...

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Detalles Bibliográficos
Autores principales: Cavarelli, Mariangela, Foglieni, Chiara, Rescigno, Maria, Scarlatti, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662319/
https://www.ncbi.nlm.nih.gov/pubmed/23606583
http://dx.doi.org/10.1002/emmm.201202232