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Ibrutinib: an evidence-based review of its potential in the treatment of advanced chronic lymphocytic leukemia
Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with a variable course, and remains an incurable disease. Frequent relapses and eventual resistance to fludarabine characterize symptomatic CLL and portends a dismal prognosis for patients. Growing evidence has shown that signaling pathwa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662532/ https://www.ncbi.nlm.nih.gov/pubmed/23717217 http://dx.doi.org/10.2147/CE.S34068 |