Ibrutinib: an evidence-based review of its potential in the treatment of advanced chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with a variable course, and remains an incurable disease. Frequent relapses and eventual resistance to fludarabine characterize symptomatic CLL and portends a dismal prognosis for patients. Growing evidence has shown that signaling pathwa...

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Detalles Bibliográficos
Autores principales: Chavez, Julio C, Sahakian, Eva, Pinilla-Ibarz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662532/
https://www.ncbi.nlm.nih.gov/pubmed/23717217
http://dx.doi.org/10.2147/CE.S34068

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