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Characterization of adipose-derived stromal/stem cells from the twitcher mouse model of krabbe disease

BACKGROUND: Krabbe disease, also known as globoid cell leukodystrophy, is an autosomal recessive neurodegenerative disease caused by the genetic deficiency of galactocerebrosidase (GALC), a lysosomal enzyme responsible for the degradation of several glycosphingolipids like psychosine and galactosylc...

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Detalles Bibliográficos
Autores principales: Zhang, Xiujuan, Semon, Julie A, Zhang, Shijia, Strong, Amy L, Scruggs, Brittni A, Gimble, Jeffrey M, Bunnell, Bruce A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662570/
https://www.ncbi.nlm.nih.gov/pubmed/23590629
http://dx.doi.org/10.1186/1471-2121-14-20