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Characterization of adipose-derived stromal/stem cells from the twitcher mouse model of krabbe disease
BACKGROUND: Krabbe disease, also known as globoid cell leukodystrophy, is an autosomal recessive neurodegenerative disease caused by the genetic deficiency of galactocerebrosidase (GALC), a lysosomal enzyme responsible for the degradation of several glycosphingolipids like psychosine and galactosylc...
Autores principales: | Zhang, Xiujuan, Semon, Julie A, Zhang, Shijia, Strong, Amy L, Scruggs, Brittni A, Gimble, Jeffrey M, Bunnell, Bruce A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662570/ https://www.ncbi.nlm.nih.gov/pubmed/23590629 http://dx.doi.org/10.1186/1471-2121-14-20 |
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