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Inhibition of ADAM-17 more effectively down-regulates the Notch pathway than that of γ-secretase in renal carcinoma
BACKGROUND: Our study is to research the effect of inhibited ADAM-17 expression through the Notch pathway in renal carcinoma. METHODS: Immunohistochemistry and western blot were used to examine the expression of ADAM-17 protein in renal cancer tissues. Proliferation and cell invasion of 786-o cells,...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662624/ https://www.ncbi.nlm.nih.gov/pubmed/23659326 http://dx.doi.org/10.1186/1756-9966-32-26 |