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Inhibition of ADAM-17 more effectively down-regulates the Notch pathway than that of γ-secretase in renal carcinoma

BACKGROUND: Our study is to research the effect of inhibited ADAM-17 expression through the Notch pathway in renal carcinoma. METHODS: Immunohistochemistry and western blot were used to examine the expression of ADAM-17 protein in renal cancer tissues. Proliferation and cell invasion of 786-o cells,...

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Detalles Bibliográficos
Autores principales:	Guo, Zhen, Jin, Xunbo, Jia, Haiyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662624/ https://www.ncbi.nlm.nih.gov/pubmed/23659326 http://dx.doi.org/10.1186/1756-9966-32-26

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