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Ikbkap/Elp1 Deficiency Causes Male Infertility by Disrupting Meiotic Progression
Mouse Ikbkap gene encodes IKAP—one of the core subunits of Elongator—and is thought to be involved in transcription. However, the biological function of IKAP, particularly within the context of an animal model, remains poorly characterized. We used a loss-of-function approach in mice to demonstrate...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662645/ https://www.ncbi.nlm.nih.gov/pubmed/23717213 http://dx.doi.org/10.1371/journal.pgen.1003516 |