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Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion

Control of human cytomegalovirus (HCMV) depends on CD8+ T cell responses that are shaped by an individual's repertoire of MHC molecules. MHC class I presentation is modulated by a set of HCMV-encoded proteins. Here we show that HCMV immunoevasins differentially impair T cell recognition of epit...

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Detalles Bibliográficos
Autores principales: Ameres, Stefanie, Mautner, Josef, Schlott, Fabian, Neuenhahn, Michael, Busch, Dirk H., Plachter, Bodo, Moosmann, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662661/
https://www.ncbi.nlm.nih.gov/pubmed/23717207
http://dx.doi.org/10.1371/journal.ppat.1003383