BcL-xL Conformational Changes upon Fragment Binding Revealed by NMR

Protein-protein interactions represent difficult but increasingly important targets for the design of therapeutic compounds able to interfere with biological processes. Recently, fragment-based strategies have been proposed as attractive approaches for the elaboration of protein-protein surface inhi...

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Detalles Bibliográficos
Autores principales: Aguirre, Clémentine, ten Brink, Tim, Walker, Olivier, Guillière, Florence, Davesne, Dany, Krimm, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662666/
https://www.ncbi.nlm.nih.gov/pubmed/23717610
http://dx.doi.org/10.1371/journal.pone.0064400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662666/
https://www.ncbi.nlm.nih.gov/pubmed/23717610
http://dx.doi.org/10.1371/journal.pone.0064400

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