Cell-Autonomous Function of Runx1 Transcriptionally Regulates Mouse Megakaryocytic Maturation

RUNX1 transcription factor (TF) is a key regulator of megakaryocytic development and when mutated is associated with familial platelet disorder and predisposition to acute myeloid leukemia (FPD-AML). We used mice lacking Runx1 specifically in megakaryocytes (MK) to characterized Runx1-mediated trans...

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Detalles Bibliográficos
Autores principales: Pencovich, Niv, Jaschek, Ram, Dicken, Joseph, Amit, Ayelet, Lotem, Joseph, Tanay, Amos, Groner, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662678/
https://www.ncbi.nlm.nih.gov/pubmed/23717578
http://dx.doi.org/10.1371/journal.pone.0064248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662678/
https://www.ncbi.nlm.nih.gov/pubmed/23717578
http://dx.doi.org/10.1371/journal.pone.0064248

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