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Pilus Phase Variation Switches Gonococcal Adherence to Invasion by Caveolin-1-Dependent Host Cell Signaling

Many pathogenic bacteria cause local infections but occasionally invade into the blood stream, often with fatal outcome. Very little is known about the mechanism underlying the switch from local to invasive infection. In the case of Neisseria gonorrhoeae, phase variable type 4 pili (T4P) stabilize l...

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Detalles Bibliográficos
Autores principales: Faulstich, Michaela, Böttcher, Jan-Peter, Meyer, Thomas F., Fraunholz, Martin, Rudel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662692/
https://www.ncbi.nlm.nih.gov/pubmed/23717204
http://dx.doi.org/10.1371/journal.ppat.1003373